Nerve Injury Mechanisms
- compression
- direct compression from displaced bone can injury neighboring nerves
- direct compression from hemorrhage post-fracture
- direct compression from prolonged positioning/immobility post-fracture
- soft-tissue inflammation/overuse can increase compression to nerve tissue
- surgical complications
- peripheral nerves for superficial sensation and sensorimotor function may be stretched or cut during operative procedures
Nerve Injury Classification
- First degree - temporary demyelination - recovery expected in 12 weeks
- Second degree - associated with more severe trauma or prolonged compression, includes more extensive demyelination and axonal degeneration; regeneration is likely and may take 6 months to a year or more
- Third degree - extent of nerve injury and demyelination is extensive - regeneration is not likely
- Fourth degree - significant nerve injury and extensive scar formation prevents any regeneration below scar area; surgical interventions for recovering function
- Fifth degree - complete nerve transection; surgical intervention to recover function
- Sixth degree - describes a combination of varying levels of function within a nerve, which may require surgical interventions to restore function
Nerve Injury Recovery
- Nature of injury
- nerve injuries that are proximal (i.e. closer to the nerve root) affect more structure and result in greater loss of function
- nerve injuries that are proximal are slower to recover due to regeneration times (0.5mm to 1 in./day) and regeneration may be incomplete
- Timing of repair
- complete laceration of nerves require surgical intervention: surgical success rate depends on timing of surgery since injury and location of nerve
- Age and motivation
- neuroplasticity and adaptability of motor and pre-motor planning and sensory reintegration is higher in the younger population
- repeated initiation, practice, feedback optimizes ability to redevelop sensorimotor pathways and motor function