FN 225: Nutrition
Noy Rathakette, Ph.D.
Health Professions Division
Lane Community College
Eugene, Oregon
FORUM Week 1: (Each week, you are required to post a reply to a question
or to post a question you have regarding the content of the class
or to "reply" to another student's posting.)

Active participation in these FORUMs will probably improve your score on Exams.

  1. This online Lecture 1B describes an ISLI working group's guidelines regarding achieving unbiased research.  Which of those guidelines do you find most important?

  2. The end of this Lecture 1B also suggests that you look at the Fats of Life website http://www.fatsoflife.com and the
    Nutritional Therapy Association
    http://www.nutritionaltherapy.com/ website.

    The
    end of this Lecture 1B asks a number of questions about the websites. 
    What is ONE answer that you found?

  3. Is there anything in either Lecture 1A or Lecture 1B or the Study Questions for Chapter 1 that you have comments or questions about?
LECTURE 1B: (a continuation of Chapter 1-Food Choices and Human Health

III Identifying Valid Nutrition Info in the News: Scientific Research


Why do we want to know how to identify valid nutrition info in the news?

We want to know how to identify "valid nutrition info in the news" so we'll have some idea who to believe.


Nutrition Today, September/October 2007
"Twilight of the Gatekeepers: An Uncomfortable Fable"
Sylvia Rowe MA and Nick Alexander BA

The above article discusses the explosion of new health and nutrition-oriented Web sites that may have been created by individuals or organizations not formally tied to the scientific community. "Internet democracy bestows on these sites, often distinguished by a particular political, philosophical, moral, or other nonscientific point of view, the same importance, credibility, and prominence as sites formerly regarded as authoritative." 

"Just as the Internet has fostered the prosperity of a citizen-based journalism, with a varied and growing assortment of 'news blogs' and the like, so has it encouraged a kind of citizen-based science movement, where publication takes place solely or primarily in cyberspace, where peer review has no accepted place".

"There is no denying that emerging computer and Internet technology has opened up a brave new world in which scientists and other thinkers can, with ever increasing speed, share their ideas and research globally. Theories can be analyzed and breakthrough conclusions reached, enhancing human health at a speed and scale never before realized.

"There is also no denying that the same technologies are creating a world in which utter nonsense or worse can do a reputable job of masquerading as scientific truth and can recruit hapless believers and followers to intellectual mischief-or worse.

"Are we heading toward a world of greater clarity or greater confusion?"


I, for one, don't know the answer to that question, but the following are some guidelines to consider when trying to decide if something is
valid nutrition information.

A.    Has Characteristics of GOOD Scientific Research.

1.    Researcher (who might not be the author) has good credentials

Usually done by someone with a doctorate (PhD) or a master's (MS) in nutrition or another related field or an MD who has advanced training in nutrition.

You can usually identify PhDs or MDs with nutrition training by their place of work (a major university with a strong nutrition program or a government agency for nutrition or health).


more later in his lecture about places of work........

It's important to ask- Who paid for the research

Bias because of who paid for the study doesn't mean it's definitely a bad study, but it's a study that certainly should be repeated to see if someone else gets the same results.

I listened to a story on the radio  that you can listen to if you'd like:


Researchers Find Bias in Nutrition Studies by Allison Aubrey, NPR Morning Edition, January 9, 2007 · A new study, co-authored by Harvard researchers and analysts from the Center for Science in the Public Interest, suggests there's a systematic bias in nutrition studies funded by food companies.

"Funding Food Science and Nutrition Research: Financial Conflicts and Scientific Integrity", The International Life Sciences Institute (ILSI) North America Conflict of Interest/Scientific Integrity Guiding Principles Working Group,

Journal of the American Dietetic Association
, May 2009, 929-936.

This
working group was organized by the non-profit International Life Sciences Institute and was supported in part by educational grants by Coca Cola, General Mills and other companies. 

ILSL is supported by industry members; government funding; and contributions from charitable foundations, corporations, and corporate foundations.

Click here for the
working groups members' credentials and places of work.

This working group proposes the following guidelines to serve as a checklist in achieving unbiased research results from industry-funded activities as well as useful guidance in public- or foundation-funded projects.

In the conduct of public/private research relationships, all relevant parties shall:
  1. NOT FAVOR A PARTICULAR OUTCOME

    "conduct or sponsor research that is factual, transparent, and designed objectively; according to accepted principles of scientific inquiry, the research design will generate an appropriately phrased hypothesis and the research will answer the appropriate questions, rather than favor a particular outcome";

  2. RETAIN CONTROL

    "require control of both the study design and the research itself to remain with scientific investigators";

  3. REFUSE PAYMENT

    "not offer or accept remuneration geared to the outcome of a research project";

  4. PUBLISH

    "prior to the commencement of studies, ensure that there is a written agreement that the investigative team has the freedom and obligation to attempt to publish the findings within some specified time frame";

  5. DISCLOSURE- 1

    "require, in publications and conference presentations, full signed disclosure of all financial interests";

  6. DISCLOSURE- 2

    "not participate in undisclosed paid authorship arrangements in industry-sponsored publications or presentations";

  7. ACCESSIBILITY

    "guarantee accessibility to all data and control of statistical analysis by investigators and appropriate auditors/reviewer"; and

  8. DISCLOSURE- 3

    "require that academic researchers, when they work in contract research organizations or act as contract researchers, make clear statements of their affiliation; require that such researchers publish only under the auspices of the contract research organization."





The above study was reported in the June 2009 issue of the Journal of the American Dietetic Association.  I like this conclusion from the study:
“The most important implication of the presented results is that health care providers should focus on modification of whole dietary patterns instead of changes in the intake of individual foods or nutrients in children."

Notice
in the next image the conflict of interest disclosure statement from the E-KINDEX study.









The above study was
also reported in the June 2009 issue of the Journal of the American Dietetic Association.  Notice in the next image the conflict of interest disclosure statement from the fish oil study.



(Incidentally, Oregon Registered Dietitian Jessie Pavlinac [shown below] is the 2009-2010 president of the American Dietetic Association.)


Now let's return to some guidelines to consider when trying to decide if something is valid nutrition information.

A.    Has Characteristics of GOOD Scientific Research.

1. (discussed above)  Researcher (who might not be the author) has good credentials

2.    When possible, double blind with a placebo
and a reasonable number of subjects were used for a long period

* Definition of placebo- NOT a real treatment but it might induce body's natural healing process
* Double blind: neither the receiver of the treatment or the   giver    of the treatment know what the person is getting
* Reasonable number:    it depends   on what is reasonable to do.  Ideally, there would be a large number of people studied, but sometimes there's not funding to study a large number.

3.    Study results reported so
others can replicate (duplicate) and

reported in respected, refereed (articles evaluated by persons with nutrition credentials) scientific journals

      

Below is an example of a respected, refereed scientific journal :
      



Articles on the cover of the above October 2004 issue of the Journal of the American Dietetic Association:

Obesity Risk and HIV-Infected Youth

Dietary Intake Change and Cancer Diagnosis

Body Image of Chronic Dieters

Parental Views  of high School Soft Drink Machines



Where in a publication can you find credentials for "referees"?

usually near the beginning of the publication

In this publication, the "referees" are called the"Editorial Board".  Notice their credentials (PhD, RD, etc.) as well as their place of work.


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Prevention Magazine, December 1980

Editor: Robert Rodale
Executive Editor: Mark Bricklin
Managing Editor: John Feltman
Assistant Managing Editor: William Gottlieb
Research Chief: Carol Baldwin
Senior Editors: Jane Kinderlehrer, John Yates
Associate Editors: Linda Shaw, Kerry Pechter, Tom Voss, Katherine Randall
Assistant Research Chief: Carol Matthews
Copy Chief: Jeanne Rogers
Art Director: Laura Tylersmith
Research Associates: Marion Wolbers, Susan Rosenkrantz, Sue Ann Gursky, Martha Capwell, Joann Williams
Research Librarian: Liz Wolbach
Head Librarian: Janet Glassman
Reader’s Service Director: Christy Kohler
Beauty Editor: Virginia Castleton
Office Manager: Carol Petrakovich
Technical Director: Mark Schwartz, PhD
Photography Director: T.L. Gettings
Photographer: Margaret Smyser

What credentials do you see in the above list of editors, etc. listed at the front of a 1980 issue of  Prevention Magazine
?


Now look below at a more recent issue.

Prevention Magazine
 Editorial Advisors (page 20) September, 2004


James W. Anderson, MD
Professor of Medicine and Clinical Nutrition, University of Kentucky College of Medicine
Kelly Brownell, PhD
Professor of Psychology, Yale University; Director of Yale Center for Eating and Weight Disorders
Judith Stern, ScD, RD
Co-director, Center for Alternative and Complementary Medicine and Professor of Nutrition and Internal Medicine at the University of California, Davis
plus 13 others

Below is a newsletter I enjoy. http://www.cspinet.org






A journal usually is a primary source of information, while a magazine [or a newsletter] is a secondary source).

What does this mean?  A primary source means that the author of the article did the research.  A secondary source means that the author is reporting about someone else's research.


Looking at the examples of publications above (Prevention, Nutrition Action Healthletter and the Journal of the American Dietetic Association), which do you think is a primary source of information and which a secondary source?

The "click here" portions of these lectures are an attempt to make them interactive and engaging, similar to classroom lectures.  It will be difficult to complete the lectures and do well on exams if you choose not to "click here".

Click here if you think Prevention is an example of a primary source.
Click here if you think Prevention is an example of a secondary source.

Click here if you think Nutrition Action Healthletter is an example of a primary source.
Click here if you think Nutrition Action Healthletter is an example of a secondary source.

Click here if you think the Journal of the American Dietetic Association is an example of a primary source.
Click here if you think the Journal of the American Dietetic Association is an example of a secondary source.

4. Broad generalizations NOT made

5. If research on animals, findings not applied directly to humans

6. If research done on specific segments of population or people living in a clinical setting, it's not applied to ALL people.

For example, if a study finds that large doses of vitamin E affect Alzheimer's patients, the researcher or author avoids implying that EVERYONE should take large doses.




B.    If research studies are discussed, they're usually one of the several types of Scientific Research Studies:


1. Case Study
- thoroughly studying ONE  INDIVIDUAL
(sometimes groups).
What is the difference between a case study and a testimonial?  A case study is done by a researcher and a testimonial is one person describing their experience, but an outside person did not observe them for research.

2. Observational Study- simply monitoring and/or collecting information. No treatment given so NO PLACEBO. COLLECTING INFO

3. Epidemiological Study (another type of Observational Study)- examines a particular large (maybe hundreds or thousands) population to determine what people's health patterns or risk factors have been OR are over time and then this is linked with incidence of disease or other health problems. These people were/are NOT given a treatment. (often retrospective, which  means it's looking at the past).

Epidemiological studies
(a) look at a large population of people
(b) often over a period of time and
(c) relate their findings to disease rates
(d) NOT given a treatment

4. Laboratory Study- study done under tightly controlled conditions. Since it's difficult to tightly control conditions for humans, these studies are usually done on      animals   or in    test tubes    .


5.  Intervention Study- (often called "clinical trials") people ARE given a treatment and the results are observed (prospective, meaning they do something and see what happens rather than looking at something that already happened, which is what epidemiological studies do).

Definition of treatment: something given (examples- a nutritional supplement/certain food/advice) OR something done (
examples- education or massage or physical therapy).
(Write in your notes the definition and also the examples.)

Study Questions and Exams will ask you to identify the type of study research a particular study is describing.  I hope the chart below will help a little.


Case
Study
Epidemiological
Study
Intervention
Study

Observational
Study
SIZE of group
1 person or 1 grp.
    large   group
(
maybe hundreds or thousands)
can be large group but not always

can be large group but not always
TREATMENT?   
  no
treatment 
     no treatment            


relate results to
     disease risk      

usually collect info over      time    



a treatment (pill, advice, therapy) often with a control group who might be given a placebo

     no treatment          

As mentioned above, intervention studies are often called "clinical trials".  This was a Register-Guard newspaper ad in April of 2009.





Watch the video clip below to help fill in the next part of the lecture outline in your packet.


12-minute Video Clip:
What Kind of Study Is This?
The two browsers that seem to be the fastest ways of accessing the video clips are Safari on a Mac and Internet Explorer on a Windows-based computer. 

A dial-up Internet connection is not fast enough to watch many parts of the
Lectures

If an approximately 12-minute movie isn't showing up just above on your computer, you may not have the latest version of QuickTime on your computer.  Click here to download the newest version of Quick Time.

Viewing the video clips works best with the following browsers:
Safari if using a Mac
Explorer if using a Windows-based computer

I didn't understand why, but Firefox does NOT work.

IV Identifying Nutrition Info that is unreliable (not valid) & that should make you suspicious 

    "Earmarks" (markers) of unreliable nutrition

1. Too good to be true
2. Suspicious about food supply
3. Only Testimonials
4. Fake credentials
5. Unpublished studies
6. Persecution claims
7. Authority not cited (Nutrition training not defined)
8. Motive: Personal gain
9. Advertisement
10. Unreliable publication (Unrefereed) OR unreliable Internet site
11. Half truths (logic without proof; in other words part is true & part is false, not known or misleading)
EXAMPLE from http://www.wp.com/queen bee (This site no longer exists)

What is Royal Jelly? According to this site, "Royal jelly is the exclusive food of the queen bee. The diet of royal jelly transforms a worker bee into a queen bee. For centuries royal jelly has been used for its extraordinary benefits to strengthen the defense system. "

Rochelle Harris, Nutritionist says "I have been a natural food enthusiast for more than 30 years during which time I have used royal jelly for energy, stamina, and strength. The Queen Bee royal jelly has made such a dramatic difference that I now recommend it to all my clients."

Why is the information about Royal Jelly an example of a half truth?

The half of the
Royal Jelly information that is true is that royal jelly IS the exclusive food of the queen bee. The diet of royal jelly transforms a worker bee into a queen bee

The half that is false, unproven or misleading is that it gives benefits to humans.  There is no evidence that it gives energy, stamina, and strength to humans.  

Rochelle Harris gave a testimonial that it helped her.   There is no evidence that it does the same thing for humans and the ad didn't cite any evidence.

When you hear of something that sounds amazing, you should look carefully for something about it is only half true.  This is a very common trick pulled by people trying to sell us something.  Something about what they're saying sounds logical so we are inclined to believe everything they're saying, making us willing to spend our money.  

Royal Jelly info: Give at least 3 reasons why it is unreliable nutrition information. (Use “Earmarks” previously listed.)

See if you can come up with three reasons.  If you have trouble, send me (or another student) a message.
V 4 Guidelines for Evaluating Nutrition Info on the Web

What the LCC library says on their website is:


It is not always easy to determine if information on the World Wide Web is credible. However, using the guidelines below will help you in making that evaluation.
  1. AUTHORITY
  2. OBJECTIVITY
  3. ACCURACY
  4. CURRENCY
At the end of these 4
Remember to ask yourself:

"Is the Web the best place for this type of information... would a print source or an electronic database be a better choice?"

Double check with a Reference Librarian if you are unsure.




I'll expand those 4 points for nutrition information:


1.    AUTHORITY. To help determine, look for recognized credentials.
What does “recognized” mean? An outside organization with rigorous standards (especially for nutrition curriculum) recognize that credential is reliable.

Is this a recognized credential? NTP (Nutritional Therapy Practitioner).  In other words, do organizations with rigorous standards (especially for curriculum) recognize that credential is reliable?

When I first saw this a few years ago, the credential was called CNT (Certified Nutrition Therapist).

Given by Nutritional Therapy Association
http://www.nutritionaltherapy.com/

Notice that the Nutritional Therapy Association is a .com.  In other words, it's a for-profit business.  That doesn't guarantee that their curriculum is bad, but I am definitely suspicious since nobody but their own business is evaluating the curriculum.

You can go to the above site and click on "Nutritional Therapist".

Cost of tuition for fall, winter and spring: $3,300
(Fall: $1100 for 2 weekends + 1 conference call
Winter: $1100 for 2 more weekends
+ 1 more conference call
Spring: $1100 for 2 more weekends + 1 more conference call)

Cost of materials: I can't tell what is now required for materials.  Can anyone else find that info on their website?

Hours of Instruction: 6 weekends plus 3 conference calls

Credentials of Eugene Instructor: no evidence of education or training besides the  
NTP credential given by the same business that employs her.

Who evaluates their curriculum?
I can find no evidence that an outside organization evaluates their curriculum and recognizes the NTP credential.

Click on this website: Fats of Life http://www.fatsoflife.com

Click where it says ABOUT US.

Do the editor and the Scientific Advisory Board have recognized credentials and
advanced training and places of work in the field of nutrition?
  • like a doctorate (PhD or DSc) in nutrition or another related field or a
  • master's (MS) in nutrition or another related field or an
  • MD with advanced training in nutrition

2.    OBJECTIVITY
Look at these two websites:
Nutritional Therapy Association http://www.nutritionaltherapy.com/ .
Fats of Life http://www.fatsoflife.com

  • Does there appear to be bias? (Sometimes a web address that ends in . com or even .org is very biased, but not always.)
  • Who is sponsoring each of these sites?

  • Is there something being sold at the site?
3.    ACCURACY. Are there misspelling?  Does it appear to be hastily developed?

Michael Scott of The Office: "Wikipedia is the best thing ever. Anyone in the world can write anything they want about any subject, so you know you are getting the best possible information."  Click here to watch the clip which lasts just about 10 seconds.


4.    CURRENCY. When was the site created?



Before you leave this lecture, you might want to do the Google search described in Study Question #42 on page 22 of your packet.  It says:

Think of a question you have about nutrition and ask that question of Google (http://www.google.com/).

Based on the 4 Guidelines above (AUTHORITY, OBJECTIVITY, ACCURACY and CURRENCY), briefly evaluate TWO of the links that Google suggests.   You will be asked 3 things:
  1. the question you asked
  2. the links you evaluated (copy the links onto a document on your computer so you can retrieve them later)
  3. the answers given
  4. your evaluation of those answers based on the 4 guidelines above and your conclusion
Here's an example of an answer:
  1. the question you asked How much Vitamin D is too much?

  2. the links you evaluated (copy the link onto a document on your computer so you can retrieve it later)

    http://www.mayoclinic.com/health/vitamin-d/AN01864

    http://www.vitamindcouncil.org/vitaminDToxicity.shtml

  3. the answers given:

    The Mayo Clinic RD states a recommendation of 200-600 IU a day of vitamin D depending on age with 2,000 IU a day the Upper Limit.

    The Vitamin D Council reports a researcher saying that human toxicity probably begins to occur after chronic daily consumption of approximately 40,000 IU/day.

  4. your evaluation of those answers based on the 4 guidelines above and your conclusion:

    As an R.D., the
    Mayo Clinic nutritionist Katherine Zeratsky appears to be an AUTHORITY (considering her credential), showing OBJECTIVITY (not selling anything or showing bias), information seems ACCURATE (references provided for peer-reviewed journals), CURRENT (posted Dec. 19, 2008).

    The Executive Director of the
    Vitamin D Council is an M.D. with no stated training that would make him an AUTHORITY on nutrition.  OBJECTIVITY of the Vitamin D Council should be questioned since links are given to sites selling vitamin D supplements.  Some information does not seem ACCURATE (or is at least misleading.... but that would be hard for someone to spot who does not have a nutrition education).  The information seems CURRENT (at least one of the peer-reviewed journal had a 2009 date).

    CONCLUSION- This is complicated information with no clear-cut answers.  In the index of our text, I looked up vitamin D and read the toxicity section.  It says that vitamin D is the most potentially toxic of all vitamins so I would be suspicious of a site that says toxicity doesn't begin until 40,000 IU when the RDA is just
200 IU (5 micrograms) if 19-50 years old
400 IU (10 micrograms) if 51-70
600 IU (15 micrograms) if 70+ years old years old

40,000 IU is 100 times the 400 IU recommendation



Jen Ferro, one of the LCC librarians found this link:
(If you have trouble viewing the 5 minute screencast, you may need to update the Flash player for your browser.)

"Evaluating Scholarly Content Online"
from the University of California- Berkeley Libraries. 
It covers:
What scholarly information is
Why scholarly information is important
How to recognize scholarly information online


The End of Lecture 1B






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CORRECT.  Prevention Magazine is an example of a secondary source of information because the authors are reporting about someone else's research.

Click here to return to the Lecture.


















































INCORRECT.  Prevention Magazine is NOT an example of a primary source of information.  Prevention Magazine is an example of a secondary source of information because the authors are reporting about someone else's research.

Click here to return to the Lecture. 


















































CORRECT.  Nutrition Action Healthletter is an example of a secondary source of information because the authors are reporting about someone else's research.

Click here to return to the Lecture.














































INCORRECT.  Nutrition Action Healthletter is NOT an example of a primary source of information.  Nutrition Action Healthletter is an example of a secondary source of information because the authors are reporting about someone else's research.

Click here to return to the Lecture.











































CORRECT.  The Journal of the American Dietetic Association is an example of a primary source of information because the authors are usually reporting about their own research.

Click here to return to the Lecture.






















































INCORRECT.  The Journal of the American Dietetic Association is NOT an example of a secondary source of information because The Journal of the American Dietetic Association is an example of a primary source of information because the authors are usually reporting about their own research.

Click here to return to the Lecture.















































The International Life Sciences Institute (ILSI) North America Conflict of Interest/Scientific Integrity Guiding Principles Working Group:
  1. Sylvia Rowe, MAT (Master of Arts in Teaching)
    President, SR Strategy LLC, Washington, DC;

  2. Nick Alexander
    Media Consultant, SR Strategy LLC, Washington, DC;

  3. Fergus M. Clydesdale, PhD (Distinguished Professor and Director of Food Science Policy Alliance, University of Massachusetts at Amherst);

  4. Rhona S. Applebaum, PhD
    Vice President/Chief Regulatory Officer, The Coca-Cola Company, Global Scientific and Regulatory Affairs, Atlanta, GA;

  5. Stephanie Atkinson, PhD
    Professor, Department of Pediatrics, McMaster University, Hamilton, ON, Canada;

  6. Richard M. Black, PhD
    Vice President, Nutrition, Kraft Foods Global, Inc, Glenview, IL;

  7. Johanna T. Dwyer, DSc, RD
    Director, Frances Stern Nutrition Center, New England Medical Center, Boston, MA;

  8. Eric Hentges, PhD
    Executive Director, ILSI North America, Washington, DC;

  9. Nancy A. Higley, PhD
    Vice President, Scientific & Regulatory Affairs, PepsiCo, Inc, Valhalla, NY;

  10. Michael LeFevre, PhD
    Professor and Director of the Human Nutrition Research Group, Utah State University, Center for Advanced Nutrition, Logan, UT;

  11. Joanne R. Lupton, PhD
    Regent's Professor, University Faculty Fellow and William W. Allen Endowed Chair in Nutrition, Texas A&M University, College of Agriculture and Life Sciences, Department of Nutrition and Food Science, College Station, TX;

  12. Sanford A. Miller, PhD
    Senior Fellow, University of Maryland Center for Food, Nutrition and Agriculture Policy, College Park, MD;

  13. Doris L. Tancredi, PhD
    Vice President, Scientific Services, Cadbury Schweppes plc, Science & Technology, Whippany, NJ;

  14. Connie M. Weaver, PhD
    Head, Department of Foods & Nutrition, Purdue University, West Lafayette, IN;

  15. Catherine E. Woteki, PhD
    Global Director of Scientific Affairs, Mars, Inc, McLean, VA;

  16. Elaine Wedral, PhD
    President, ILSI North America, Washington, DC).
Click here to return to the lecture.

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