Nerve Injury Mechanisms

  • compression
    • direct compression from displaced bone can injury neighboring nerves
    • direct compression from hemorrhage post-fracture
    • direct compression from prolonged positioning/immobility post-fracture
    • soft-tissue inflammation/overuse can increase compression to nerve tissue
  • surgical complications
    • peripheral nerves for superficial sensation and sensorimotor function may be stretched or cut during operative procedures 

Nerve Injury Classification

  • First degree - temporary demyelination - recovery expected in 12 weeks
  • Second degree - associated with more severe trauma or prolonged compression, includes more extensive demyelination and axonal degeneration; regeneration is likely and may take 6 months to a year or more
  • Third degree - extent of nerve injury and demyelination is extensive - regeneration is not likely
  • Fourth degree - significant nerve injury and extensive scar formation prevents any regeneration below scar area; surgical interventions for recovering function
  • Fifth degree - complete nerve transection; surgical intervention to recover function
  • Sixth degree - describes a combination of varying levels of function within a nerve, which may require surgical interventions to restore function

 

Nerve Injury Recovery

  • Nature of injury
    • nerve injuries that are proximal (i.e. closer to the nerve root) affect more structure and result in greater loss of function
    • nerve injuries that are proximal are slower to recover due to regeneration times (0.5mm to 1 in./day) and regeneration may be incomplete
  • Timing of repair
    • complete laceration of nerves require surgical intervention: surgical success rate depends on timing of surgery since injury and location of nerve
  • Age and motivation
    • neuroplasticity and adaptability of motor and pre-motor planning and sensory reintegration is higher in the younger population
    • repeated initiation, practice, feedback optimizes ability to redevelop sensorimotor pathways and motor function